Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of a number of myeloma. Its synthesis or study is essential for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor from the synthesis of abiraterone acetate, a drug used in the treatment method of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound in the synthesis of imatinib, a drug that targets specific forms of most cancers, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for instance breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the production approach and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is utilised to deal with breast cancer, and these intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist used in the cure of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of 3-d]pyrimodin-5-yl)ethyl]benzoic acid paclitaxel, a chemotherapy drug effective in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the therapy of colorectal most cancers and smaller cell lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, TBTU which have different programs, including antiviral Qualities.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to control blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of varied gluconic acid derivatives, which are Employed in foodstuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication made use of to control sort two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).